Topical Antibiotics

Topical antibiotics are the mainstream drugs used in mild to moderate acne, with evidence of papules and pustules which are lesions describing an inflammatory process, most likely believed secondary to Propionibacterium acnes exposure.

Clindamycin Phosphate (Dalacin T)

Clindamycin phosphate, also known as Dalacin T, is a combined anti-inflammatory with an ability to halt bacterial growth. It has bacteriostatic action. The large drawback to this effective medication, is that in patients with bowel problems, such as in patients with inflammatory bowel disease, there is a small risk of developing Clostridium difficile colitis. Clindamycin is well-known to predispose patients to C.difficile colitis. Any diarrhea after clindamycin use should be followed up by a physician to rule out C.difficile infection.

Topical Antibiotic and Benzoyl Peroxide Combinations

There are a couple of antibiotic and comedolytic combinations. These include: Benzamycin, which consists of Benzoyl peroxide and Erythromycin; BenzaClin, consisting of Benzoyl peroxide and Clindamycin.