Flutamide

If spironolactone is contraindicated, an alternative androgen receptor blocker is flutamide. Flutamide is A non-steroidal androgen receptor blocker, which is very expensive, and in contrast to spironolactone has many gastrointestinal side effects, such as bloating, changing bowel habits, and effects on the liver. Liver enzymes have to be frequently monitored while on this medication.